Types
- The main symptom is intense pruritis and dry skin
- Typical morphology and distribution ( Flexural lichenification or linearity in adults; facial and extensor involvement in infants and children)
- Chronic or chronically relapsing dermatitis
- Personal or family history of atopic dermatitis( e.g asthma, allergic rhinitis, atopic dermatitis)
The course of atopic dermatitis may be divided into three phases: Infantile phase, Childhood phase, and Adult phase
- Infantile phase: Face and scalp involvement is common as well as the extensor surfaces of the extremities and trunk
- Childhood phase: Eczema is observed on the flexural surfaces, including the neck, antecubital or popliteal fossae, wrists, and ankles
- Adult phase: Lichenification of the flexures and hands commonly occurs
Associated findings
- Atopic triad of asthma, allergic rhinitis, and atopic dermatitis that is linked to allergen triggered IgE, White dermographism ( transiently blanched skin), Dermatographism, Keratosis pillaris( keratinized hair follicles), xerosis, Ichthyosis
Important signs
- Hertoghe’s sign( thinning of lateral eyebrows), Hyperkeratosis, and hyperpigmentation producing a dirty neck appearance. Atopic individuals often exhibit perioral, perinasal, and periorbital pallor “headlight sign”
Differential diagnosis
- Seborrheic dermatitis – Lesions are usually dry in atopic dermatitis and more greasy in seborrhic dermatitis. The most useful distinguishing feature in seborrhic dermatitis is the increased number of lesions on the axilla
- Psoriasis: onset is usually after adolescent years and lesions are typically covered with white silvery scales, located on the extensor surface
- Infectious conditions: Mycoses, scabies