Types
- Main symptom is intense pruritis and dry skin
- Typical morphology and distribution ( Flexural lichenification or linearity in adults; facial and extensor involvement in infants and children)
- Chronic or chronically relapsing dermatitis
- Personal or family history of atopic dermatitis( e.g asthma, allergic rhinitis, atopic dermatitis)
Course of atopic dermatitis may be divided in three phases: Infantile phase, Childhood phase and Adult phase
- Infantile phase: Face and scalp involvement is common as well as the extensor surfaces of the extremities and trunk
- Childhood phase: Eczema is observed on the flexural surfaces, including the neck, antecubital or popliteal fossae, wrists and ankles
- Adult phase: Lichenification of the flexures and hands commonly occurs
- Associated findings: Atopic triad of asthma, allergic rhinitis, and atopic dermatitis that is linked to allergen triggered IgE , White dermographism ( transiently blanched skin), Dermatographism, Keratosis pillaris ( keratinized hair follicles) , xerosis, Ichthyosis
- Important signs: Hertoghe’s sign( thinning of lateral eyebrows), Hyperkeratosis and hyper pigmentation producing a dirty neck appearance. Atopic individuals often exhibit perioral, perinasal, and periorbital pallor “headlight sign”
Differential diagnosis
- Seborrheic dermatitis – Lesions are usually dry in atopic dermatitis and more greasy in seborrhic dermatitis. The most useful distinguishing feature in seborrhic dermatitis is the increased number of lesions on the axilla
- Psoriasis : onset is usually after adolescent years and lesions are typically covered with white silvery scales , located on extensor surface
- Infectious conditions : Mycoses, scabies