BRONCHIECTASIS

Description

  • Bronchiectasis (broncos – airways, ectasia – dilation ) is an irreversible and abnormal dilation in the bronchial tree that is generally caused by cycles of bronchial inflammation in addition to mucous plugging and progressive airway destruction
  • The most important clinical finding is a chronic cough with copious mucopurulent sputum. Other symptoms may include dyspnoea, rhinosinusitis, and haemoptysis
  • It affects all ages, although the prevalence increase with age. Bronchiectasis should be suspected in patients with a chronic cough that produces large amounts of sputum

Etiology

Pulmonary infections (i.e. bacterial, viral, fungal)

Bronchial narrowing or other forms of obstruction

  • COPD
  • Aspiration
  • Tumours
  • α1-antitrypsin deficiency
  • congenital bronchiectasis, tracheomalacia, bronchogenic cyst

Disorders of secretion clearance or mucous plugging

  • Cystic fibrosis (CF) 
  • Primary ciliary dyskinesia
  • Allergic bronchopulmonary aspergillosis
  • Kartagener syndrome
  • Smoking: associated with poor ciliary motility

Immunodeficiency

  • Chronic inflammatory diseases
  • Rheumatoid arthritis
  • Sjogren’s syndrome
  • Crohn’s disease

Types

  • Productive cough, the most common complaint, is almost invariably present and leads to chronic bronchitis
  • Cough is long standing, copious, purulent with sputum that is worse in the morning
  • Bronchiectasis sicca (dry) with no sputum production and episodic haemoptysis may occur due to localised upper lobe bronchiectasis and autogenic drainage
  • Increased cough, sputum volume and purulence, wheeze, fever, haemoptysis and chest pain define the presence of acute exacerbation
  • Rhinosinusitis
  • Dyspnoea
  • Haemoptysis – is usually mild or self-limiting, but severe haemorrhage that requires embolization may occur 
  • Nonspecific symptoms ( fatigue, weight loss, pallor due to anaemia)
  • Clubbing of nails (uncommon)

On Auscultation

  • Crackles and rhonchi
  • Wheezing
  • Bronchophony

Investigation

Chest X-Ray

  • Best initial test , shows tram track lines ( characteristic sign of bronchial wall thickening)
  • Thin-walled cysts (i.e. dilated bronchi forming sacs), possibly with air-fluid levels
  • Honeycombing in late-stage bronchiectasis

High-resolution computer tomography (HRCT)

  • Is the confirmatory test
  • Dilated bronchi with thickened walls; possible signet-ring appearance and tram track lines
  • Cysts, especially at bronchial ends in lower lobes, and honeycombing

Other tests

  • Sputum culture and smear: to determine infectious etiology (bacteria, mycobacteria, and fungi)
  • CBC with differential: ↑ WBCs, ↑ neutrophils
  • Pulmonary function tests: findings consistent with obstructive pulmonary disease
  • Bronchoscopy

Treatments

  • Bronchiectasis is a permanent anatomical malformation and therefore cannot be cured.
  • Address the underlying symptom
  • Goal of Treatment is to reduce disease progression, maintain and improve lung function, reduce infective exacerbations and improve the quality of life
  • Airway clearing techniques – Breathing techniques
  • Hydration – Adequate intake of oral fluid
  • Surgical resection of bronchiectatic lung or lobectomy
  • Lung transplantation should be considered in severe disease

Internal Medicines

  • Dashamoola katutraya kashaya
  • Nayopayam kashaya
  • Vyagradhi kashaya
  • Svasananda rasa
  • Dhanwantara gutika
  • Kasthuryadi gutika
  • Dashamoolarishta
  • Kanakasava + Vasarishta
  • Dashamoola rasayana
  • Kooshmanda rasayana
  • Indukanta Ghrita

Procedures 

  • Pranayama
  • Karpooradi taila - ext application on chest
  • Busa pinda sweda

Department

Kayachikitsa

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