Types

• Antinuetrophil cytoplasmic antibodies (ANCA) are antibodies produced by the immune system that mistakenly target and attack specific proteins within neutrophils. ANCA may be present in several auto immune disorders that cause inflammation, tissue damage, and organ failure. Few types of systemic vasculitis are associated with the production...

Description

• Negative : <7.0 U/ml
• Positive : >15.0U/ml
• Equivocal : 7.0-15.0U/ml

When to get Tested

• When there is s/s that suggest systemic auto immune vasculitis (initially non specific s/s like fever, fatigue , weight loss, muscle and/or joint aches, night sweats and as the disease progress s/s like red itchy eyes or pink eye, hearing loss, runny nose , granuloma, proteinuria)

Elevated Level

• Wegener’s granulomatosis
• Polyangitis overlap syndrome
• Crohn’s disease
• Churg strauss syndrome
• Glomerulonephritis

Decreased Level