Benign invasion of the endometrium into the myometrium due to hyperplasia of the endometrial basal layer producing a diffusely enlarged uterus (Endometriosis internal)
Both glandular and stromal components of the endometrium are involved
Associated with myometrial hypertrophy and may be either diffuse or focal
Peak incidence at 35-50 years
Types
Dysmenorrhoea
Heavy menstrual bleeding
Prolonged bleeding cycles
Chronic pelvic pain
Severe and increasing abdominal pain throughout the month
Back pain
Dyspareunia
Infertility
Investigation
Clinical diagnosis
Pelvic examination –reveals an enlarged, tender, and boggy uterus
Ultrasonography (TVS) - Focal or diffuse myometrial bulkiness, typically of the posterior wall
Myometrial Biopsy
CA-125 (elevated in adenomyosis)
MRI
Treatments
Surgical
Progestins or cyclic oestrogen and progestin
Definitive treatment - Total hysterectomy, with or without ovarian conservation
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