Primary amenorrhoea – absence of menstruation by 16 years of age in the presence of normal secondary sexual characters, or by 14 years of age in the absence of secondary sexual characters
Secondary amenorrhoea – absence of menstruation for six months (three normal cycles) with previously normal menstruation or absence of menstruation for 12 or more months following oligomenorrhoea
Cryptomenorrhoea - Periodic shedding of endometrium and bleeding, but due to obstruction in the genital tract menstrual blood fails to come out
Causes of cryptomenorrhoea- Congenital (Imperforate hymen, Transverse vaginal septum) & Acquired (Stenosis of Cervix following amputation, deep cauterization, etc; Secondary vaginal atresia)
If prolactin level > 100 ng/ mL, X ray/CT/MRI for diagnosing pituitary adenoma
Progesterone challenge test–
The patient is administered progesterone tablets for 5 to 10 days
If withdrawal bleeding occurs - Intact HPO axis, normal oestrogen secretion and there is progesterone deficiency Diagnosis – ovulation issues and the common cause is PCOS
If there is no withdrawal bleeding - Do Estrogen – Progesterone challenge test. Give OCP or oestrogen tablets for 25 days + progesterone tablets from day 15 to 25. If bleeding occurs, it denotes deficiency of oestrogen as well
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