FIBROID UTERUS

Description

  • Fibroids are benign hormone-sensitive uterine neoplasms and the most common cause of hysterectomy 
  • Peak incidence during the reproductive age; between 35 – 45 years
  • It is predominantly an oestrogen dependent tumor and does not occur before menarche and the fibroid regress after menopause
  • Increased growth of fibroid can be seen in pregnancy and can cause several complications

Types of fibroids

  • Intramural / Interstitial - lie within the myometrial wall of the uterus. Subsequently, they grow outwards or inwards
  • Subserous - localized in the outer uterine wall and grows outward towards the peritoneal cavity and is covered by peritoneum
  • Submucous - localized directly below the endometrial layer ( uterine mucosa)
  • Cervical fibroids
  • Broad ligament fibroids

Etiology

  • Nulliparity
  • Early menarche
  • Obesity
  • PCOS
  • Family history
  • High-fat diet 
  • Genetic alterations
  • Oral contraceptives

Types

  • Most of the fibroids are asymptomatic and diagnosed accidentally during USG, laparoscopy, etc.
  • Menstrual irregularities – Menorrhagia, Metrorrhagia (more common with subserous fibroids)
  • Dysmenorrhoea
  • Infertility
  • Pressure symptoms – constipation, dysuria, retention of urine, increased frequency of micturition, etc.
  • Dyspareunia
  • Reproductive abnormalities (miscarriage, preterm labour, IUGR, recurrent pregnancy loss)
  • Lower abdominal or pelvic pain
  • Abdominal enlargement

Investigation

  • USG - Abdominal, transvaginal or pelvic USG
  • Laparoscopy
  • Hysteroscopy – to access submucosal fibroids
  • Endometrial biopsy
  • Hysterosalpingography 
  • MRI – to evaluate uterus and ovaries for potentially complicated surgical cases and visually differentiate between leiomyomas, adenomyomas, and adenomyosis

Treatments

For symptomatic fibroids 

  • Medication to control symptoms
  • Medication aimed at shrinking tumours
  • Ultrasound fibroid destruction
  • Surgically aided methods to reduce blood supply of fibroids
  • Myomectomy or radiofrequency ablation
  • Hysterectomy
  • Treatment for infection and anemia

 Medications-

  • Oral contraceptive pills
  • GnRH agonists
  • Anti-hormonal drugs (mifepristone)
  • Antifibrinolytics
  • Non-steroidal anti-inflammatory agents
  • Progesterone receptor modulator 

Surgery 

  • Myomectomy
  • Hysterectomy
  • Uterine artery embolization
  • Uterine artery ligation
  • Radiofrequency ablation
  • Endometrial ablation

Ayurvedic Treatment

Internal Medicines

  • Bleeding phase- give haemostatic treatment initially

Later

  • Varanadi Kashaya
  • Chitraka grandyadi Kashaya
  • Munditaka Kashaya
  • Saptasara kashaya
  • Trayantyadi Kashaya – in bleeding fibroids
  • Decoction of Varuna twak + shigru
  • Kumaryasava
  • Abhayarishta
  • Asokarishta
  • Kanchanara Guggulu
  • Chandraprabha vati
  • Gomutra Hareetaki
  • Dashamoola Hareetaki

Procedures

  • Snehana - Varanadi Ghrita, Pippalyadi Anuvasana Taila, Tila Taila, Dashamoola Taila 
  • In bleeding fibroids- Guggulu Thiktaka Gritha, Maha Thiktaka Gritha 
  • Vamana
  • Virechana - in bleeding fibroids
  • Vasti Erandamoola Kashaya, Dashamoola Kashaya, Punarnavaashtaka Kashaya, Varuna Shigru Kashaya, Lekhana Mahakashya 
  • Uttara Vasti – above said Sneha preparations and Lekhana Mahakashya sidha Taila 

Department

Prasoothi & Stree Roga

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