HYPERPROLACTINEMIA

Description

  • Hyperprolactinemia is a condition of elevated serum prolactin. Prolactin is a 198-amino acid protein produced in the lactotroph cells of the anterior pituitary gland
  • The primary function of prolactin is to enhance breast development during pregnancy and to induce lactation

Etiology

Prolactin (> 100mcg/L)

  • Altered metabolism
  • Liver failure
  • Renal failure
  • Carcinoma
  • Gonadoblastoma
  • Ovarian dermoid cyst
  • Renal cell carcinoma
  • Teratoma
  • Breastfeeding
  • Hypothyroidism
  • Medications like – OCP’s, Antipsychotics, Antidepressants, Histamine, H2 blockers, Opiates, Antihypertensive drugs, etc.

Prolactin > 100ng/ML

  • Empty sella syndrome
  • Pituitary adenoma

Types

  • Galactorrhoea
  • Headache
  • Visual disturbances
  • Irregular bleeding or anovulation
  • Infertility

Investigation

  • Serum Prolactin levels
  • Normal fasting value is generally less than 25-30 ng/ml
  • Prolactin stimulation test – to rule out prolactinoma
  • Cranial contrast MRI – to rule out pituitary adenomas 

Treatments

  • Dopamine agonists
  • Surgery for Macroadenoma
  • Monitor progression of macroadenoma by MRI and prolactin level
  • Craniotomy/ Transsphenoidal resection if needed

Ayurvedic Treatment

Internal Medicines

  • Aragwadhadi Kashaya
  • Thiktaka kashaya
  • Kanchanara Guggulu 
  • Sidharthaka Taila
  • Punarnavasava

Procedures

  • Snehapana - Sidharthaka Taila
  • Vamana
  • Thakradhara
  • Sthana bandhana with Jathi Kusuma

Department

Female Infertility

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