CA125 is a mucin like glycoprotein. It is a surface antigen associated with non mucinous epithelial ovarian cancer. The protein is sloughed or secreted from the surface of the ovarian cancer cells into the serum. It is a useful tumour marker for evaluating therapy and monitoring disease status in patients under treatment for ovarian cancer....
When to get Tested
When a woman has a pelvic mass to help determine the cause
When Ovarian cancer treatment is started to compare against future measurements.
Non mucinous epithelial ovarian carcinoma
Fallopian tube tumours
Squamous cell carcinoma of vulva or cervix
Several Gynaecological conditions can cause a false positive result. Endometriosis , benign ovary cysts , first trimester of pregnancy , and pelvic inflammatory disease all produce higher levels of CA 125.
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