Types

• Alkaline phosphatase is an enzyme in all tissues. Tissues with particularly high concentrations include liver, bile ducts, placenta and bone. ALP is one of the enzymes present in serum that is capable of transporting phosphate groups across cell membrane.
• The serum or plasma ALP is estimated to investigate diseases of the liver or b...

Description

Males : 53 – 128 U/L

Females : 42 -98 U/L

Infants : 150 – 420 U/L Children : 100 -320 U/L

When to get Tested

• when there is s/s suggesting a bone disorder (Bone and or joint pain, Increased frequency of fractures , Deformed bones).
• When there is Symptoms of Bile duct obstruction (Severe abdominal pain in the right upper quadrant or center of abdomen , pain that spreads to the back or right shoulder blade , Nausea , Abdominal pain linked with eating a fatty meal).
• When there is s/s of liver disease ( weakness, fatigue, loss of appetite, nausea, vomiting, Jaundice, Dark urine, light coloured stools, pruritus, swelling in the legs and ankles, tendency to bruise easily)

Elevated Level

• Biliary obstruction
• Bone disease
• Healing fracture 
• Hepatitis
• Hyperthyroidism
• Hyperparathyroidism
• Leukemia
• Liver diseases
• Cirrhosis 
• Gilbert syndrome
• Fatty metamorphosis of liver
• Sepsis
• infectious mononucleosis
• cytomegalovirus infections
• Postoperative cholestasis
• Pancreatitis
• carcinoma of pancreas,cystic fibrosis
• Anaemia 
• Pulmonary infarct
• Fanconi syndrome
• Osteoblastic bone cancers
• Osteomalacia
• Paget's disease
• Rickets
• Hypervitaminosis D
• Familial hyperphosphatasemia

Decreased Level

• Malnutrition
• Protein deficiency
• Pernicious anemia
• Hypophosphatasia
• Hypothyroidism
• Severe chronic nephritis 
• Celiac disease