ANTI-HEPATITIS B ENVELOPE ANTIGEN TOTAL ANTIBODY
Description
OD Ratio
- Positive : <1.01
- Equivocal : 1.01-1.10
- Negative : >1.11
Clinical significance
- Antibodies developed against hepatitis envelope antigen (HbeAg). Anti Hbe is the second antibody to appear and is associated with the rapid clearance of HbeAg. Later, Anti Hbe antibodies decline and persist only for a few months or year if there is no active viral replication. If HbeAg is considered a specific marker of infectivity, the presence of anti HbeAg antibody in blood is recognized to be a clinical sign of recovery from infection to convalescence.
- Development of Anti Hbe antibody represents minimum viral replication
- Indicates decreasing infectivity, suggesting good prognosis, and resolution of acute infection
- In serologic window period, association of Anti-Hbe with Anti Hbc confirms recent acute infection
When to get tested
- In a known case of hepatitis B infection- to find out severity of infection
- To find out resolution of infection
- To predict the carrier state of hepatitis B infection
Elevated level
Decreased level
Profile
ALL TEST
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