Cortisol is the most abundant circulating steroid and the major glucocorticoid secreted by the adrenal complex. Physiologically effective in anti inflammatory activity and blood pressure maintenance, it is also involved in gluconeogenesis, calcium absorption and the secretion of gastric acid and pepsin.
Cortisol levels are often mea...
At 8 AM : 5.0 -25 mg/dl
At 4 PM : 2.5 -12.5 mg/dl
When to get Tested
When symptoms are suggestive of High level of cortisol and Cushing syndrome (Hypertension, high blood sugar, obesity, Fragile skin, Purple streaks on the abdomen, Muscle wasting, Osteoporosis)
When symptoms are suggestive of Low levels of cortisol or Adrenal Insufficiency or Addisons disease (weight loss, muscle weakness, fatigue, Low blood pressure, Abdominal pain, Dark patches in skin)
Ectopic ACTH-producing tumours
Secondary adrenal Insufficiency
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