HDL (HIGH DENSITY LIPOPROTEIN)

Description

  • Males : > 40 mg/dl Females > 50 mg/dl

Clinical significance

  • Commonly called good cholesterol HDL is not secreted into the circulation as mature lipoprotein but is assembled in the blood from components derived from intestine , liver , cell membranes and triglyceride rich lipoprotein during lipolysis . 
  • HDL acts as a scavenger by removing cholesterol from peripheral cells such as smooth muscles . It also provides protective benefits from its ability to influence the binding and absorption of LDL by cells such as smooth muscles . 
  • Women tend to have higher cholesterol than men. In general , an increased risk for heart diseases including heart attack occurs when the HDL level is less than 40 mg/dl. More specifically , men are at a particular risk if their HDL is below 37 mg/dl and women if their HDL is below 47 mg/dl

When to get tested

  • As a screening test for adults with no risk factors for heart disease
  • When a person has one or more risk factors for heart disease( Cigarette smoking, Being overweight or Obese, old age , Pre existing heart disease, diabetes)

Elevated level

  • An HDL 60 mg/dl or above helps protect against heart disease.

Decreased level

  • Low HDL levels may indicate an increased risk of Atherosclerotic heart disease .

Profile

Cardiac

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