THYROGLOBULIN/TG
Description
- 0-55 ng/ml
Clinical significance
- Thyroglobulin is a protein that is normally confined to the thyroid gland. It is synthesized in the follicular cells of the Thyroid gland under the influence of Thyrotropin and represents the precursor to Thyroxine and other iodothyronines. It is an aid in identifying the presence or absence of functioning of thyroid tissue.
- The major clinical application for measurement of this prohormone is derived from the fact that functioning thyroid tissue appears to be the only source of circulating Thyroglobulin. It is a non specific indicator of a Thyroid dysfunction and highly reliable tumor marker in thyroid cancer patient.
When to get tested
- When a person has symptoms of Hyperthyroidism
- When there is suspicion of Graves disease or Thyroiditis
- Prior to Surgical removal of Thyroid Gland for Cancer and also after completion of treatment to determine
- whether any cancerous residual thyroid tissue may be left behind
Elevated level
- In patients with Thyroid carcinoma
- Moderate to very high thyroglobulin levels are seen in many thyro normal patients also.
- In patients with metastases of Thyroid cancer
Decreased level
Profile
Thyroid
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