Triglycerides
Description
- Desirable : <150 mg/dl
- Borderline high : 150 -199 mg/dl
- High : 200 -499 mg/dl
- Very high : >500 mg/dl
Clinical significance
- Triglycerides are a storage form of lipid found in blood. It is measured as a reflection of fat (lipid) ingestion and metabolism , or as a part of an evaluation of coronary risk factors .
- Triglycerides comprise the largest proportion of fats in the diet , in the adipose tissue and in the blood. Triglycerides move via the blood from the gut to adipose tissue for storage .Immediately after a meal triglycerides appear in the blood as the major constituent of chylomicrons.
- The chylomicron remnant is taken up by the liver so that it disappears from the blood in 2-3 hours . The remaining triglycerides and additional triglycerides synthesized within the liver are then re packaged as VLDL and secreted into the blood from liver
When to get tested
- To evaluate risk of heart disease in healthy adults
- When risk factors for Heart disease has been identified (Cigarette smoking, being overweight or obese, unhealthy diet, Pre existing heart disease, Diabetes, High Blood Pressure)
Elevated level
- Associated with a higher risk for heart disease and stroke
- Cirrhosis
- Familial hyperlipoproteinemia (rare)
- Hypothyroidism
- Low protein in diets and high carbohydrates
- Poorly controlled diabetes
- Nephrotic syndrome
- Pancreatitis
- Drugs like Cholestyramine, Estrogens and Oral contraceptives, Beta blockers
Decreased level
- Malabsorption syndrome
- Malnutrition
- Hyperthyroidism
- Low fat diet
- Drugs - Ascorbic acid, Clofibrate and Colestipol
Profile
Lipid
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